Chlamydophila psittaci seropositivity and serum levels of soluble intercellular adhesion molecule-1 in farmers.

نویسندگان

  • Concettina Fenga
  • Anna Cacciola
  • Venerando Rapisarda
  • Giovanna Spatari
  • Sebastiano Calimeri
  • Paola Lucia Minciullo
  • Giuseppe Di Pasquale
  • Sebastiano Gangemi
چکیده

Chlamydophila infection is known as an occupational hazard to veterinarians, farmers, poultry workers. Serum levels of the soluble Intercellular Adhesion Molecule-1 (sIC AM-1), is associated with C. seropositivity. Since no data about IC AM-1 levels and C. psittaci infection are known, the aim of this work was to assess if chronic persistent C. psittaci infection constantly stimulates the expression of sIC AM-1, independent of the characteristic symptoms of ornithosis. C. psittaci seropositivity and serum concentrations of sIC AM-1 were investigated in 30 farmers and 20 age-matched healthy public employees as controls. Increased serum sIC AM-1 levels were found in the group of farmers exposed to infectious risk compared to controls, and the serum concentrations of sIC AM-1 was significantly correlated with a high IgG titre against C. psittaci. It is therefore possible to suggest a sIC AM-1 measurement for use as a tool to verify the development of C. psittaci chronic infection in an occupational setting.

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عنوان ژورنال:
  • Annals of agricultural and environmental medicine : AAEM

دوره 15 2  شماره 

صفحات  -

تاریخ انتشار 2008